| Drug Name: | Acitretin |
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| Drug Class: | Retinoid |
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| Mechanism of Action: | Acitretin is a synthetic retinoid that binds to nuclear receptors and modulates gene expression, leading to normalization of keratinocyte differentiation and reduction of inflammation. |
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| Use: | - Treatment of severe psoriasis
- Maintenance therapy for psoriasis
- Treatment of severe keratinization disorders
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| Side Effects: | - Dry skin
- Dry lips
- Hair loss
- Elevated liver enzymes
- Hyperlipidemia
- Teratogenicity (should not be used during pregnancy)
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| Contraindications: | - Pregnancy
- Hypersensitivity to retinoids
- Severe hepatic or renal impairment
- Hyperlipidemia
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| Specialty: | |
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