Drug Name: | Allopurinol |
---|
Drug Class: | Xanthine oxidase inhibitor |
---|
Mechanism of Action: | - Inhibits the enzyme xanthine oxidase, which is responsible for the conversion of hypoxanthine to xanthine and then to uric acid
- Reduces the production of uric acid in the body
|
---|
Use: | - Prevention and treatment of gout and hyperuricemia
- Prevention of uric acid nephropathy in patients undergoing chemotherapy or radiation therapy
|
---|
Side Effects: | - Skin rash
- Nausea and vomiting
- Diarrhea
- Headache
- Dizziness
- Hypersensitivity reactions (e.g. Stevens-Johnson syndrome)
|
---|
Contraindications: | - Hypersensitivity to allopurinol
- Severe liver or kidney disease
- Pregnancy and breastfeeding
|
---|
Specialty: | - Rheumatology
- Oncology
- Nephrology
|
---|