Drug Name:Alteplase
Drug Class:Thrombolytic agent
Mechanism of Action:
  • Converts plasminogen to plasmin, which breaks down fibrin clots
  • Activates the fibrinolytic system
Use:
  • Acute ischemic stroke
  • Acute myocardial infarction
  • Pulmonary embolism
  • Acute peripheral arterial occlusion
Side Effects:
  • Bleeding
  • Allergic reactions
  • Hypotension
  • Fever
  • Nausea and vomiting
Contraindications:
  • Active bleeding
  • Recent surgery or trauma
  • Severe uncontrolled hypertension
  • History of intracranial hemorrhage
  • Known bleeding diathesis
Specialty:
  • Emergency Medicine
  • Cardiology
  • Neurology
  • Vascular Surgery