| Drug Name: | Amikacin |
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| Drug Class: | Aminoglycoside Antibiotic |
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| Mechanism of Action: | - Binds to the bacterial 30S ribosomal subunit, inhibiting protein synthesis and causing bacterial cell death
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| Use: | - Treatment of serious infections caused by susceptible gram-negative bacteria, including Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae
- Used in combination with other antibiotics for the treatment of tuberculosis
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| Side Effects: | - Nephrotoxicity
- Ototoxicity
- Neuromuscular blockade
- Hypersensitivity reactions
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| Contraindications: | - Hypersensitivity to aminoglycosides
- Renal impairment
- Pregnancy
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| Specialty: | - Infectious Disease
- Critical Care
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