Drug Name: | Amphotericin |
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Drug Class: | Antifungal |
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Mechanism of Action: | Binds to ergosterol in fungal cell membranes, causing membrane permeability and cell death |
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Use: | - Treatment of severe systemic fungal infections
- Prophylaxis in immunocompromised patients
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Side Effects: | - Nephrotoxicity
- Infusion-related reactions (fever, chills, hypotension)
- Electrolyte imbalances (hypokalemia, hypomagnesemia)
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Contraindications: | - Hypersensitivity to amphotericin or its components
- Severe renal impairment
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Specialty: | - Infectious Disease
- Hematology
- Oncology
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