Drug Name: | Apraclonidine |
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Drug Class: | Alpha-2 Adrenergic Agonist |
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Mechanism of Action: | - Stimulates alpha-2 adrenergic receptors in the eye, reducing aqueous humor production and increasing uveoscleral outflow
- May also reduce sympathetic tone in the eye, leading to decreased intraocular pressure
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Use: | - Treatment of open-angle glaucoma and ocular hypertension
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Side Effects: | - Ocular burning, stinging, or discomfort
- Dry mouth
- Headache
- Dizziness
- Fatigue
- Hypotension
- Bradycardia
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Contraindications: | - Hypersensitivity to apraclonidine or any component of the formulation
- Use with MAO inhibitors or tricyclic antidepressants
- Severe cardiovascular disease
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Specialty: | |
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