Drug Name:Aripiprazole
Drug Class:Atypical Antipsychotic
Mechanism of Action:
  • Partial agonist at dopamine D2 and serotonin 5-HT1A receptors
  • Antagonist at serotonin 5-HT2A receptor
Use:
  • Schizophrenia
  • Bipolar disorder
  • Major depressive disorder (adjunctive therapy)
  • Autism spectrum disorder (irritability)
Side Effects:
  • Akathisia
  • Insomnia
  • Headache
  • Nausea
  • Weight gain
  • Tremor
Contraindications:
  • Hypersensitivity to aripiprazole
  • Severe CNS depression
  • QT prolongation
Specialty:
  • Psychiatry
  • Neurology