Drug Name: | Artemisinin |
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Drug Class: | Antimalarial |
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Mechanism of Action: | - Artemisinin and its derivatives are endoperoxides that generate free radicals in the presence of iron, which damage the parasite's cell membrane and organelles, leading to its death.
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Use: | - Treatment of uncomplicated and severe malaria caused by Plasmodium falciparum
- Used in combination with other antimalarial drugs to prevent the development of resistance
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Side Effects: | - Nausea
- Vomiting
- Abdominal pain
- Dizziness
- Headache
- Insomnia
- Allergic reactions
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Contraindications: | - Hypersensitivity to artemisinin or any of its derivatives
- First trimester of pregnancy
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Specialty: | - Infectious Disease
- Tropical Medicine
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