Drug Name:Azathioprine
Drug Class:Immunosuppressant
Mechanism of Action:
  • Inhibits DNA synthesis and cell proliferation
  • Suppresses immune system by inhibiting T-cell function
Use:
  • Prevention of organ rejection in transplant patients
  • Treatment of autoimmune diseases such as rheumatoid arthritis, lupus, and Crohn's disease
Side Effects:
  • Nausea and vomiting
  • Diarrhea
  • Increased risk of infection
  • Bone marrow suppression
  • Liver toxicity
Contraindications:
  • Pregnancy
  • Breastfeeding
  • Active infection
  • Hypersensitivity to azathioprine
Specialty:
  • Rheumatology
  • Transplant medicine
  • Gastroenterology