Drug Name: | Azathioprine |
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Drug Class: | Immunosuppressant |
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Mechanism of Action: | - Inhibits DNA synthesis and cell proliferation
- Suppresses immune system by inhibiting T-cell function
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Use: | - Prevention of organ rejection in transplant patients
- Treatment of autoimmune diseases such as rheumatoid arthritis, lupus, and Crohn's disease
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Side Effects: | - Nausea and vomiting
- Diarrhea
- Increased risk of infection
- Bone marrow suppression
- Liver toxicity
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Contraindications: | - Pregnancy
- Breastfeeding
- Active infection
- Hypersensitivity to azathioprine
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Specialty: | - Rheumatology
- Transplant medicine
- Gastroenterology
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