Drug Name:Bumetanide
Drug Class:Loop diuretic
Mechanism of Action:
  • Inhibits the Na-K-2Cl cotransporter in the ascending loop of Henle
  • Increases excretion of sodium, chloride, and water
Use:
  • Edema associated with heart failure, hepatic or renal disease
  • Hypertension
Side Effects:
  • Hypokalemia
  • Dehydration
  • Hypotension
  • Ototoxicity
Contraindications:
  • Anuria
  • Hypersensitivity to sulfonamides
Specialty:
  • Cardiology
  • Nephrology