Drug Name: | Carbimazole |
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Drug Class: | Thioamide antithyroid agent |
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Mechanism of Action: | - Inhibits the synthesis of thyroid hormones by blocking the iodination of tyrosine residues in thyroglobulin
- Reduces the conversion of T4 to T3 in peripheral tissues
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Use: | - Treatment of hyperthyroidism
- Preparation for thyroidectomy or radioactive iodine therapy
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Side Effects: | - Hypothyroidism
- Agranulocytosis
- Rash
- Joint pain
- Nausea
- Vomiting
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Contraindications: | - Hypersensitivity to carbimazole or other thioamides
- Pregnancy and breastfeeding
- Severe liver disease
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Specialty: | - Endocrinology
- Internal Medicine
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