Drug Name:Cefotaxime
Drug Class:Third-generation cephalosporin
Mechanism of Action:
  • Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs)
Use:
  • Treatment of serious infections caused by susceptible bacteria
  • Meningitis
  • Septicemia
  • Lower respiratory tract infections
  • Urinary tract infections
  • Intra-abdominal infections
Side Effects:
  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Hypersensitivity reactions
  • Superinfection
Contraindications:
  • Hypersensitivity to cephalosporins
  • History of anaphylaxis to penicillins or other beta-lactams
Specialty:
  • Infectious Disease
  • Critical Care
  • Emergency Medicine
  • Internal Medicine
  • Pediatrics