Drug Name: | Cinacalcet |
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Drug Class: | Calcimimetic agent |
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Mechanism of Action: | - Binds to and activates the calcium-sensing receptor on the parathyroid gland, leading to a decrease in parathyroid hormone (PTH) secretion
- Reduces serum calcium and phosphorus levels by decreasing PTH secretion
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Use: | - Treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis
- Treatment of hypercalcemia in patients with parathyroid carcinoma or primary hyperparathyroidism
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Side Effects: | - Nausea
- Vomiting
- Diarrhea
- Headache
- Hypotension
- Hypocalcemia
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Contraindications: | - Hypersensitivity to cinacalcet
- Hypocalcemia
- Severe hepatic impairment
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Specialty: | - Nephrology
- Endocrinology
- Oncology
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