Drug Name: | Crizanlizumab |
---|
Drug Class: | Monoclonal antibody |
---|
Mechanism of Action: | - Binds to P-selectin, preventing platelet-endothelial cell adhesion and subsequent vaso-occlusion
|
---|
Use: | - Prevention of vaso-occlusive crises in patients with sickle cell disease
|
---|
Side Effects: | - Nausea
- Back pain
- Fever
- Arthralgia
- Diarrhea
- Abdominal pain
|
---|
Contraindications: | |
---|
Specialty: | |
---|