Drug Name:Cyclophosphamide
Drug Class:Alkylating agent
Mechanism of Action:
  • Cross-links DNA strands, preventing cell division and replication
  • Immunosuppressive effects
Use:
  • Treatment of various cancers (e.g. lymphoma, leukemia, breast cancer)
  • Treatment of autoimmune diseases (e.g. lupus, rheumatoid arthritis)
Side Effects:
  • Nausea and vomiting
  • Hair loss
  • Increased risk of infection
  • Hemorrhagic cystitis
  • Infertility
  • Increased risk of secondary cancers
Contraindications:
  • Pregnancy
  • Breastfeeding
  • Severe bone marrow suppression
  • Active infections
Specialty:
  • Oncology
  • Rheumatology