Drug Name: | Darunavir |
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Drug Class: | Protease Inhibitor |
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Mechanism of Action: | Inhibits the protease enzyme, preventing the cleavage of viral polyproteins and the formation of mature infectious viral particles |
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Use: | - Treatment of HIV-1 infection in adults and pediatric patients
- Used in combination with other antiretroviral agents
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Side Effects: | - Nausea
- Diarrhea
- Headache
- Rash
- Abdominal pain
- Elevated liver enzymes
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Contraindications: | - Hypersensitivity to darunavir or any component of the formulation
- Co-administration with drugs that are highly dependent on CYP3A for clearance and for which elevated plasma concentrations are associated with serious and/or life-threatening events
- Severe hepatic impairment
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Specialty: | - Infectious Disease
- HIV/AIDS
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