Drug Name:Desmopressin
Drug Class:Antidiuretic hormone
Mechanism of Action:
  • Selective agonist of vasopressin V2 receptors in renal collecting ducts
  • Increases water reabsorption and decreases urine output
Use:
  • Treatment of diabetes insipidus
  • Treatment of nocturnal enuresis
  • Treatment of von Willebrand disease
  • Treatment of mild to moderate hemophilia A
Side Effects:
  • Headache
  • Nausea
  • Abdominal cramps
  • Hyponatremia
  • Water intoxication
Contraindications:
  • Hypersensitivity to desmopressin
  • Severe renal impairment
  • Hyponatremia
  • Heart failure
Specialty:
  • Endocrinology
  • Pediatrics
  • Hematology