Drug Name: | Diamorphine |
---|
Drug Class: | Opioid analgesic |
---|
Mechanism of Action: | - Binds to mu-opioid receptors in the CNS
- Inhibits the release of neurotransmitters such as substance P, GABA, and dopamine
- Produces analgesia, sedation, and euphoria
|
---|
Use: | - Management of severe pain
- Palliative care
- Acute pain relief in myocardial infarction and pulmonary edema
|
---|
Side Effects: | - Respiratory depression
- Sedation
- Nausea and vomiting
- Constipation
- Hypotension
- Bradycardia
- Confusion
- Dizziness
- Itching
- Urinary retention
|
---|
Contraindications: | - Hypersensitivity to opioids
- Respiratory depression
- Severe asthma
- Paralytic ileus
- Head injury
- Increased intracranial pressure
- Severe hepatic or renal impairment
- Pregnancy
|
---|
Specialty: | - Pain management
- Palliative care
- Emergency medicine
|
---|