Drug Name: | Doxorubicin |
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Drug Class: | Anthracycline antibiotic |
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Mechanism of Action: | - Inhibits DNA and RNA synthesis by intercalating into DNA strands
- Generates free radicals that damage DNA and cell membranes
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Use: | - Treats various types of cancer, including breast, lung, ovarian, and bladder cancer
- Used in combination with other chemotherapy drugs
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Side Effects: | - Nausea and vomiting
- Hair loss
- Mouth sores
- Decreased blood cell counts
- Cardiotoxicity
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Contraindications: | - Pregnancy and breastfeeding
- Severe liver or kidney disease
- Previous treatment with maximum cumulative dose of doxorubicin
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Specialty: | |
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