| Drug Name: | Entacapone |
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| Drug Class: | Catechol-O-methyltransferase (COMT) inhibitor |
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| Mechanism of Action: | - Inhibits the enzyme COMT, which breaks down dopamine in the brain
- Increases the availability of dopamine in the brain
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| Use: | - Used in combination with levodopa/carbidopa to treat Parkinson's disease
- Helps to reduce the wearing-off effect of levodopa
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| Side Effects: | - Nausea
- Vomiting
- Diarrhea
- Dizziness
- Orthostatic hypotension
- Dyskinesia
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| Contraindications: | - Hypersensitivity to entacapone
- Severe liver disease
- Pheochromocytoma
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| Specialty: | |
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