Drug Name: | Ergometrine |
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Drug Class: | Uterotonic agent |
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Mechanism of Action: | - Binds to and activates alpha-adrenergic, dopaminergic, and serotonergic receptors in the smooth muscle of the uterus
- Induces sustained contractions of the uterus
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Use: | - Prevention and treatment of postpartum hemorrhage
- Induction of labor
- Management of incomplete or inevitable abortion
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Side Effects: | - Nausea and vomiting
- Headache
- Hypertension
- Uterine cramping
- Chest pain
- Dyspnea
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Contraindications: | - Hypersensitivity to ergot alkaloids
- Hypertension
- Preeclampsia
- Eclampsia
- Severe hepatic or renal impairment
- History of cardiovascular disease
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Specialty: | |
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