Drug Name:Esomeprazole
Drug Class:Proton Pump Inhibitor
Mechanism of Action:Reduces gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells
Use:
  • Treatment of gastroesophageal reflux disease (GERD)
  • Healing and maintenance of erosive esophagitis
  • Treatment of gastric ulcers
  • Management of Zollinger-Ellison syndrome
Side Effects:
  • Headache
  • Nausea
  • Abdominal pain
  • Diarrhea
  • Flatulence
  • Dizziness
Contraindications:
  • Hypersensitivity to esomeprazole or other proton pump inhibitors
  • Co-administration with drugs that require gastric acidity for absorption (e.g., ketoconazole, iron salts)
Specialty:
  • Gastroenterology
  • Internal Medicine
  • Family Medicine