| Drug Name: | Fluconazole |
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| Drug Class: | Antifungal |
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| Mechanism of Action: | - Inhibits fungal cytochrome P450-dependent enzymes, leading to accumulation of fungal ergosterol and inhibition of cell membrane synthesis
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| Use: | - Treatment of systemic and superficial fungal infections
- Prophylaxis of fungal infections in immunocompromised patients
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| Side Effects: | - Nausea
- Vomiting
- Abdominal pain
- Diarrhea
- Headache
- Rash
- Hepatotoxicity
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| Contraindications: | - Hypersensitivity to fluconazole or other azole antifungals
- Concomitant use of terfenadine, astemizole, cisapride, pimozide, quinidine, or erythromycin
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| Specialty: | - Infectious Disease
- Internal Medicine
- Oncology
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