Drug Name: | Flumazenil |
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Drug Class: | Benzodiazepine antagonist |
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Mechanism of Action: | Competitive antagonist at the benzodiazepine binding site on the GABA-A receptor |
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Use: | - Reversal of sedation and respiratory depression caused by benzodiazepines
- Diagnosis and treatment of benzodiazepine overdose
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Side Effects: | - Nausea
- Vomiting
- Dizziness
- Headache
- Agitation
- Seizures (rare)
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Contraindications: | - Hypersensitivity to flumazenil or benzodiazepines
- Use in patients with a history of seizures or benzodiazepine dependence
- Use in patients who have received long-term benzodiazepine therapy
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Specialty: | - Emergency Medicine
- Anesthesiology
- Critical Care Medicine
- Toxicology
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