Drug Name:Frusemide
Drug Class:Loop diuretic
Mechanism of Action:
  • Inhibits the reabsorption of sodium and chloride ions in the ascending loop of Henle
  • Increases the excretion of water, sodium, chloride, magnesium, and calcium
Use:
  • Edema associated with heart failure, liver cirrhosis, and renal disease
  • Hypertension
Side Effects:
  • Dehydration
  • Electrolyte imbalances (hypokalemia, hyponatremia, hypomagnesemia, hypocalcemia)
  • Hypotension
  • Ototoxicity
  • Hyperuricemia
  • Hyperglycemia
Contraindications:
  • Hypersensitivity to frusemide or sulfonamides
  • Anuria
  • Severe electrolyte depletion
Specialty:
  • Cardiology
  • Nephrology