| Drug Name: | Gentamycin |
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| Drug Class: | Aminoglycoside Antibiotic |
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| Mechanism of Action: | - Inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit
- Causes misreading of mRNA, leading to inhibition of protein synthesis and ultimately bacterial cell death
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| Use: | - Treatment of serious infections caused by susceptible gram-negative bacteria
- Used in combination with other antibiotics for empiric therapy of sepsis
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| Side Effects: | - Nephrotoxicity
- Ototoxicity
- Neuromuscular blockade
- Allergic reactions
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| Contraindications: | - Hypersensitivity to gentamycin or other aminoglycosides
- Pre-existing renal or auditory impairment
- Myasthenia gravis
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| Specialty: | - Infectious Disease
- Critical Care
- Pharmacy
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