Drug Name: | Imiquimod |
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Drug Class: | Immune response modifier |
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Mechanism of Action: | - Stimulates the immune system by activating toll-like receptor 7 (TLR7) on dendritic cells and macrophages
- Induces the production of cytokines, including interferon-alpha, tumor necrosis factor-alpha, and interleukin-12
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Use: | - Topical treatment of external genital and perianal warts caused by human papillomavirus (HPV)
- Topical treatment of actinic keratosis (AK), a precancerous skin condition
- Topical treatment of superficial basal cell carcinoma (sBCC), a type of skin cancer
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Side Effects: | - Local skin reactions, such as redness, itching, burning, and flaking
- Flu-like symptoms, such as fever, fatigue, and headache
- Nausea, vomiting, and diarrhea
- Rarely, severe allergic reactions
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Contraindications: | - Hypersensitivity to imiquimod or any component of the formulation
- Pregnancy and breastfeeding
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Specialty: | |
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