Drug Name:Infliximab
Drug Class:TNF-alpha inhibitor
Mechanism of Action:
  • Binds to TNF-alpha and prevents it from binding to its receptors, thereby reducing inflammation
Use:
  • Treatment of autoimmune diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, and ankylosing spondylitis
Side Effects:
  • Increased risk of infections
  • Infusion reactions such as fever, chills, and headache
  • Development of antibodies against the drug
  • Increased risk of lymphoma and other cancers
Contraindications:
  • Active infections
  • Heart failure
  • Multiple sclerosis
  • Pregnancy and breastfeeding
Specialty:
  • Rheumatology
  • Gastroenterology
  • Dermatology