Drug Name:Isotretinoin
Drug Class:Retinoid
Mechanism of Action:
  • Inhibits sebaceous gland activity
  • Reduces inflammation
  • Normalizes keratinization
Use:
  • Severe acne
  • Rosacea
  • Hidradenitis suppurativa
Side Effects:
  • Dry skin and mucous membranes
  • Photosensitivity
  • Muscle and joint pain
  • Depression and suicidal ideation
  • Teratogenicity
Contraindications:
  • Pregnancy
  • Hypersensitivity to isotretinoin or vitamin A
  • Liver disease
Specialty:
  • Dermatology
  • Endocrinology
  • Psychiatry