Drug Name:Lenvatinib
Drug Class:Tyrosine kinase inhibitor
Mechanism of Action:Inhibits multiple receptor tyrosine kinases, including VEGFR, FGFR, PDGFR, RET, and KIT
Use:
  • Treatment of advanced renal cell carcinoma
  • Treatment of unresectable hepatocellular carcinoma
  • Treatment of radioactive iodine-refractory differentiated thyroid cancer
Side Effects:
  • Hypertension
  • Fatigue
  • Diarrhea
  • Nausea
  • Decreased appetite
  • Weight loss
  • Proteinuria
  • Hand-foot syndrome
  • QT prolongation
Contraindications:
  • Pregnancy
  • Breastfeeding
  • Severe hepatic impairment
Specialty:
  • Oncology
  • Hepatology
  • Endocrinology