Drug Name: | Macrolides |
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Drug Class: | Antibiotics |
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Mechanism of Action: | - Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit
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Use: | - Treatment of respiratory tract infections (pneumonia, bronchitis, sinusitis)
- Treatment of skin and soft tissue infections
- Treatment of sexually transmitted infections (chlamydia, gonorrhea)
- Prophylaxis for endocarditis in dental procedures for patients with certain heart conditions
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Side Effects: | - Gastrointestinal upset (nausea, vomiting, diarrhea)
- Hepatotoxicity
- QT prolongation
- Allergic reactions (rash, anaphylaxis)
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Contraindications: | - Hypersensitivity to macrolides
- Concomitant use with certain medications (e.g. statins, antiarrhythmics) that can increase the risk of QT prolongation
- Severe hepatic impairment
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Specialty: | - Infectious Disease
- Pulmonology
- Dermatology
- Obstetrics and Gynecology
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