Drug Name: | Mannitol |
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Drug Class: | Osmotic diuretic |
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Mechanism of Action: | - Increases osmotic pressure of glomerular filtrate
- Inhibits reabsorption of water and electrolytes in the proximal tubule
- Increases urine output
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Use: | - Reduces intracranial pressure and cerebral edema
- Reduces intraocular pressure
- Prevents acute renal failure in certain conditions
- Used as a diagnostic aid in measuring glomerular filtration rate
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Side Effects: | - Fluid and electrolyte imbalances
- Dehydration
- Hypotension
- Nausea and vomiting
- Headache
- Blurred vision
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Contraindications: | - Anuria
- Severe dehydration
- Pulmonary congestion or edema
- Active intracranial bleeding
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Specialty: | - Neurology
- Ophthalmology
- Nephrology
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