Drug Name: | Mercaptopurine |
---|
Drug Class: | Antimetabolite |
---|
Mechanism of Action: | - Inhibits DNA and RNA synthesis
- Incorporates into DNA and RNA, leading to cell death
|
---|
Use: | - Leukemia
- Crohn's disease
- Ulcerative colitis
|
---|
Side Effects: | - Nausea and vomiting
- Diarrhea
- Bone marrow suppression
- Hepatotoxicity
- Pancreatitis
|
---|
Contraindications: | - Hypersensitivity to mercaptopurine
- Pregnancy
- Breastfeeding
- Active infection
|
---|
Specialty: | |
---|