Drug Name:Mercaptopurine
Drug Class:Antimetabolite
Mechanism of Action:
  • Inhibits DNA and RNA synthesis
  • Incorporates into DNA and RNA, leading to cell death
Use:
  • Leukemia
  • Crohn's disease
  • Ulcerative colitis
Side Effects:
  • Nausea and vomiting
  • Diarrhea
  • Bone marrow suppression
  • Hepatotoxicity
  • Pancreatitis
Contraindications:
  • Hypersensitivity to mercaptopurine
  • Pregnancy
  • Breastfeeding
  • Active infection
Specialty:
  • Oncology
  • Gastroenterology