Drug Name:Mesalamine
Drug Class:Aminosalicylate
Mechanism of Action:
  • Inhibits prostaglandin and leukotriene synthesis
  • Inhibits NF-kB activation
  • Scavenges free radicals
Use:
  • Ulcerative colitis
  • Crohn's disease
Side Effects:
  • Headache
  • Nausea
  • Abdominal pain
  • Diarrhea
  • Flatulence
  • Rash
Contraindications:
  • Hypersensitivity to salicylates
  • Severe renal impairment
  • Severe hepatic impairment
Specialty:
  • Gastroenterology
  • Internal Medicine