Drug Name:Mesalazine
Drug Class:Aminosalicylates
Mechanism of Action:
  • Inhibits prostaglandin and leukotriene synthesis
  • Inhibits NF-kB activation
  • Scavenges free radicals
Use:
  • Ulcerative colitis
  • Crohn's disease
Side Effects:
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Rash
Contraindications:
  • Hypersensitivity to mesalazine or salicylates
  • Severe renal impairment
  • Severe hepatic impairment
Specialty:
  • Gastroenterology
  • Internal Medicine