Drug Name:Methadone
Drug Class:Opioid Analgesic
Mechanism of Action:
  • Binds to mu-opioid receptors in the CNS
  • Inhibits the release of neurotransmitters such as dopamine and norepinephrine
Use:
  • Pain management
  • Opioid addiction treatment
Side Effects:
  • Sedation
  • Nausea and vomiting
  • Constipation
  • Respiratory depression
  • Hypotension
  • QT prolongation
Contraindications:
  • Hypersensitivity to methadone
  • Respiratory depression
  • Severe bronchial asthma
  • Paralytic ileus
  • Acute or severe bronchial asthma
  • Use of MAO inhibitors
Specialty:
  • Pain Management
  • Addiction Medicine