Drug Name:Mirabegron
Drug Class:Beta-3 adrenergic agonist
Mechanism of Action:
  • Selective agonist of the beta-3 adrenergic receptor in the bladder
  • Relaxes the detrusor smooth muscle during the storage phase of the urinary bladder fill-void cycle
Use:
  • Treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency
Side Effects:
  • Headache
  • Nausea
  • Hypertension
  • Urinary tract infection
  • Increased heart rate
Contraindications:
  • Severe uncontrolled hypertension
  • Urinary retention
  • Gastric retention
Specialty:
  • Urology
  • Family Medicine
  • Internal Medicine