Drug Name: | Naproxen |
---|
Drug Class: | Nonsteroidal anti-inflammatory drug (NSAID) |
---|
Mechanism of Action: | Inhibits the activity of cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins that cause pain, inflammation, and fever. |
---|
Use: | - Relief of pain and inflammation associated with various conditions such as osteoarthritis, rheumatoid arthritis, gout, menstrual cramps, and headache.
- Fever reduction.
|
---|
Side Effects: | - Gastrointestinal effects such as nausea, vomiting, dyspepsia, and abdominal pain.
- Cardiovascular effects such as increased risk of heart attack and stroke.
- Renal effects such as fluid retention, edema, and kidney damage.
- Hematologic effects such as anemia and bleeding disorders.
- Hepatic effects such as liver damage and hepatitis.
|
---|
Contraindications: | - Hypersensitivity to naproxen or other NSAIDs.
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
- Active gastrointestinal bleeding or ulceration.
- Severe renal impairment or failure.
- Severe hepatic impairment or failure.
- Third trimester of pregnancy.
|
---|
Specialty: | - Rheumatology
- Pain management
- Primary care
- Emergency medicine
|
---|