Drug Name:Nicorandil
Drug Class:Potassium channel opener
Mechanism of Action:
  • Activates ATP-sensitive potassium channels in smooth muscle cells
  • Causes hyperpolarization and relaxation of smooth muscle cells
  • Dilates coronary arteries and peripheral arterioles
Use:
  • Angina pectoris
  • Heart failure
Side Effects:
  • Headache
  • Dizziness
  • Flushing
  • Nausea
  • Vomiting
  • Hypotension
  • Tachycardia
Contraindications:
  • Hypersensitivity to nicorandil
  • Severe hypotension
  • Cardiogenic shock
  • Obstructive hypertrophic cardiomyopathy
  • Severe aortic stenosis
Specialty:
  • Cardiology