Drug Name: | Nicorandil |
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Drug Class: | Potassium channel opener |
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Mechanism of Action: | - Activates ATP-sensitive potassium channels in smooth muscle cells
- Causes hyperpolarization and relaxation of smooth muscle cells
- Dilates coronary arteries and peripheral arterioles
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Use: | - Angina pectoris
- Heart failure
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Side Effects: | - Headache
- Dizziness
- Flushing
- Nausea
- Vomiting
- Hypotension
- Tachycardia
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Contraindications: | - Hypersensitivity to nicorandil
- Severe hypotension
- Cardiogenic shock
- Obstructive hypertrophic cardiomyopathy
- Severe aortic stenosis
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Specialty: | |
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