Drug Name:Nortriptyline
Drug Class:Tricyclic antidepressant
Mechanism of Action:
  • Inhibits reuptake of norepinephrine and serotonin in the CNS
  • Blocks histamine and acetylcholine receptors
Use:
  • Major depressive disorder
  • Neuropathic pain
  • Migraine prophylaxis
Side Effects:
  • Dry mouth
  • Constipation
  • Blurred vision
  • Urinary retention
  • Orthostatic hypotension
  • Weight gain
  • Sedation
  • Cardiac arrhythmias
Contraindications:
  • Recent myocardial infarction
  • Narrow-angle glaucoma
  • Severe liver disease
  • Hypersensitivity to tricyclic antidepressants
Specialty:
  • Psychiatry
  • Neurology