Drug Name: | Omeprazole |
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Drug Class: | Proton pump inhibitor |
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Mechanism of Action: | - Inhibits the H+/K+ ATPase enzyme in the gastric parietal cells, reducing acid secretion
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Use: | - Treatment of gastroesophageal reflux disease (GERD)
- Treatment of peptic ulcer disease
- Treatment of Zollinger-Ellison syndrome
- Prevention of stress ulcers in critically ill patients
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Side Effects: | - Headache
- Nausea
- Diarrhea
- Abdominal pain
- Flatulence
- Vitamin B12 deficiency
- Hypomagnesemia
- Increased risk of bone fractures
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Contraindications: | - Hypersensitivity to omeprazole or other proton pump inhibitors
- Co-administration with drugs that require acidic pH for absorption (e.g. ketoconazole, iron supplements)
- Severe hepatic impairment
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Specialty: | - Gastroenterology
- Internal medicine
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