Drug Name:Ondansetron
Drug Class:5-HT3 receptor antagonist
Mechanism of Action:Blocks serotonin receptors in the brain and gut, reducing nausea and vomiting
Use:
  • Prevention and treatment of nausea and vomiting caused by chemotherapy, radiation therapy, and surgery
  • Prevention and treatment of postoperative nausea and vomiting
  • Off-label use for nausea and vomiting caused by other conditions
Side Effects:
  • Headache
  • Constipation
  • Diarrhea
  • Dizziness
  • Fatigue
  • Flushing
  • Hiccups
  • Muscle cramps
  • Rash
Contraindications:
  • Hypersensitivity to ondansetron or other 5-HT3 receptor antagonists
  • Use with apomorphine due to risk of profound hypotension and loss of consciousness
Specialty:
  • Oncology
  • Anesthesiology
  • Gastroenterology
  • Emergency Medicine