Drug Name: | Phenobarbitone |
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Drug Class: | Barbiturate |
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Mechanism of Action: | - Enhances the activity of GABA, an inhibitory neurotransmitter in the brain
- Binds to the GABA-A receptor, increasing the duration of chloride channel opening
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Use: | - Treatment of seizures and epilepsy
- Sedation and anesthesia
- Alcohol withdrawal
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Side Effects: | - Drowsiness
- Dizziness
- Ataxia
- Nausea and vomiting
- Respiratory depression
- Hypotension
- Dependence and withdrawal symptoms
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Contraindications: | - Hypersensitivity to barbiturates
- Porphyria
- Respiratory depression
- Severe liver disease
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Specialty: | - Neurology
- Anesthesiology
- Psychiatry
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