Drug Name:Phenothiazines
Drug Class:Antipsychotic
Mechanism of Action:
  • Blockade of dopamine receptors in the brain
  • Blockade of serotonin receptors in the brain
  • Blockade of histamine receptors in the brain
Use:
  • Treatment of schizophrenia
  • Treatment of bipolar disorder
  • Treatment of severe anxiety
  • Treatment of severe nausea and vomiting
Side Effects:
  • Drowsiness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Weight gain
  • Tardive dyskinesia
  • Neuroleptic malignant syndrome
Contraindications:
  • Hypersensitivity to phenothiazines
  • Coma
  • Severe central nervous system depression
  • Liver disease
  • Blood dyscrasias
Specialty:
  • Psychiatry
  • Emergency medicine
  • Oncology