Drug Name: | Piperacillin-Tazobactam |
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Drug Class: | Antibiotic |
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Mechanism of Action: | - Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins
- Tazobactam inhibits bacterial beta-lactamases, which can break down piperacillin
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Use: | - Treatment of moderate to severe infections caused by susceptible gram-negative and gram-positive bacteria
- Commonly used for intra-abdominal infections, skin and soft tissue infections, and pneumonia
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Side Effects: | - Nausea, vomiting, diarrhea
- Headache, dizziness
- Rash, itching
- Hypersensitivity reactions
- Increased risk of Clostridium difficile infection
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Contraindications: | - Hypersensitivity to penicillins or beta-lactam antibiotics
- History of severe allergic reactions to any beta-lactam antibiotic
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Specialty: | - Infectious Disease
- Critical Care
- Emergency Medicine
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