Drug Name: | Procainamide |
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Drug Class: | Class I antiarrhythmic agent |
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Mechanism of Action: | - Blocks sodium channels in cardiac cells, slowing conduction and prolonging the refractory period
- Also has weak anticholinergic and alpha-adrenergic blocking effects
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Use: | - Treatment of ventricular arrhythmias
- Management of supraventricular arrhythmias
- May be used in Wolff-Parkinson-White syndrome
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Side Effects: | - Nausea, vomiting, diarrhea
- Hypotension
- QT prolongation
- Torsades de pointes
- Blood dyscrasias
- Lupus-like syndrome
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Contraindications: | - Complete heart block
- Myasthenia gravis
- Systemic lupus erythematosus
- Hypersensitivity to procainamide or other local anesthetics
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Specialty: | - Cardiology
- Emergency Medicine
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