Drug Name:Prochlorperazine
Drug Class:Phenothiazine antipsychotic
Mechanism of Action:
  • Blocks dopamine and serotonin receptors in the brain
  • Also has antiemetic and anticholinergic effects
Use:
  • Treatment of schizophrenia and other psychotic disorders
  • Management of severe nausea and vomiting
  • Migraine headache relief
Side Effects:
  • Drowsiness
  • Dizziness
  • Dry mouth
  • Blurred vision
  • Constipation
  • Tardive dyskinesia (with long-term use)
Contraindications:
  • Hypersensitivity to prochlorperazine or other phenothiazines
  • Comatose states
  • CNS depression
  • Severe hypotension
  • Severe liver or cardiac disease
Specialty:
  • Psychiatry
  • Gastroenterology
  • Neurology