Drug Name: | Promethazine |
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Drug Class: | Antihistamine, Antiemetic, Sedative |
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Mechanism of Action: | Blocks histamine H1 receptors, antagonizes dopamine D2 receptors, and has anticholinergic properties |
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Use: | - Relief of allergic symptoms such as itching, runny nose, and sneezing
- Prevention and treatment of nausea and vomiting
- Sedation and relief of anxiety
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Side Effects: | - Drowsiness
- Dry mouth
- Blurred vision
- Constipation
- Urinary retention
- Confusion
- Tremors
- Seizures (rare)
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Contraindications: | - Hypersensitivity to promethazine or any of its components
- Comatose states
- Severe respiratory depression
- Narrow-angle glaucoma
- Pyloroduodenal obstruction
- Stenosing peptic ulcer
- Bladder neck obstruction
- Bone marrow depression
- Reye's syndrome
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Specialty: | - Allergy and Immunology
- Emergency Medicine
- Gastroenterology
- Internal Medicine
- Neurology
- Oncology
- Pediatrics
- Psychiatry
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