Drug Name: | Pyridostigmine |
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Drug Class: | Acetylcholinesterase inhibitor |
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Mechanism of Action: | - Inhibits the breakdown of acetylcholine by acetylcholinesterase, leading to increased levels of acetylcholine in the synaptic cleft
- Enhances neuromuscular transmission and improves muscle strength
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Use: | - Myasthenia gravis
- Reversal of neuromuscular blockade
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Side Effects: | - Nausea
- Vomiting
- Diarrhea
- Abdominal cramps
- Excessive salivation
- Sweating
- Miosis
- Bradycardia
- Hypotension
- Muscle cramps
- Weakness
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Contraindications: | - Hypersensitivity to pyridostigmine or other cholinesterase inhibitors
- Mechanical obstruction of the gastrointestinal or urinary tract
- Bradycardia
- Intestinal or urinary tract obstruction
- Asthma
- Epilepsy
- Parkinson's disease
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Specialty: | |
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