Drug Name:Ranibizumab
Drug Class:Anti-VEGF (vascular endothelial growth factor) monoclonal antibody
Mechanism of Action:
  • Binds to and inhibits VEGF-A, a protein that promotes angiogenesis and vascular permeability
  • Reduces abnormal blood vessel growth and leakage in the eye
Use:
  • Treatment of neovascular (wet) age-related macular degeneration
  • Treatment of macular edema following retinal vein occlusion
  • Treatment of diabetic macular edema
  • Treatment of diabetic retinopathy
Side Effects:
  • Eye pain
  • Blurred vision
  • Increased intraocular pressure
  • Conjunctival hemorrhage
  • Eye redness
  • Eye irritation
  • Headache
  • Nausea
Contraindications:
  • Hypersensitivity to ranibizumab or any component of the formulation
  • Active or suspected ocular or periocular infection
  • Uncontrolled glaucoma
Specialty:
  • Ophthalmology